PRJEB58194 (f1_direct) RefSeq functional annotations

Descriptions and gene biotypes come directly from GCF_963853765.1 / RS_2024_06. This is annotation and ranking, not ontology or pathway enrichment.

F1 Direct Higher Fdr Lt 0.05

Genes: 1; RefSeq-characterized descriptions: 1 (100.0%).

  • LOC105347149 (NCBI:GeneID:105347149): NAD-dependent protein deacetylase Sirt6 (log2FC=0.87; adjusted p=0.0404)

F1 Direct Lower Fdr Lt 0.05

Genes: 16; RefSeq-characterized descriptions: 9 (56.2%).

  • LOC105344419 (NCBI:GeneID:105344419): protein GrpE (log2FC=-2.08; adjusted p=0.000127)
  • LOC117684421 (NCBI:GeneID:117684421): protein starmaker (log2FC=-1.61; adjusted p=0.00192)
  • LOC105339864 (NCBI:GeneID:105339864): WAG22 antigen (log2FC=-2.99; adjusted p=0.00381)
  • LOC117689738 (NCBI:GeneID:117689738): glycine-rich protein 1 (log2FC=-2.32; adjusted p=0.00439)
  • LOC105325539 (NCBI:GeneID:105325539): caveolin-3-like (log2FC=-3.19; adjusted p=0.0167)
  • LOC105326991 (NCBI:GeneID:105326991): dentin sialophosphoprotein (log2FC=-1.60; adjusted p=0.0204)
  • LOC105330462 (NCBI:GeneID:105330462): shematrin-like protein 2 (log2FC=-3.63; adjusted p=0.0204)
  • LOC105334609 (NCBI:GeneID:105334609): collagen alpha-2(I) chain (log2FC=-1.94; adjusted p=0.0439)
  • LOC105337241 (NCBI:GeneID:105337241): GRB10-interacting GYF protein 2-like (log2FC=-1.29; adjusted p=0.0496)

Gene-biotype over-representation

One-sided hypergeometric tests compare each significant direction with all genes having DESeq2 results; Benjamini-Hochberg adjustment covers both directions and all biotypes.

Many oyster loci retain automated or uncharacterized RefSeq labels. Functional claims should be based on formal ontology/pathway enrichment or orthology-aware analysis rather than names alone.