PRJNA852380 (vibrio_12h) RefSeq functional annotations

Descriptions and gene biotypes come directly from GCF_963853765.1 / RS_2024_06. This is annotation and ranking, not ontology or pathway enrichment.

Vibrio 12H Higher Fdr Lt 0.05

Genes: 859; RefSeq-characterized descriptions: 730 (85.0%).

  • LOC105318026 (NCBI:GeneID:105318026): tumor necrosis factor receptor superfamily member 11A (log2FC=4.30; adjusted p=1.15e-36)
  • LOC105320719 (NCBI:GeneID:105320719): melatonin receptor type 1A-like (log2FC=1.87; adjusted p=5.26e-29)
  • LOC105347306 (NCBI:GeneID:105347306): myeloid differentiation primary response protein MyD88-like (log2FC=3.84; adjusted p=1.25e-27)
  • LOC105321257 (NCBI:GeneID:105321257): proline-rich transmembrane protein 1 (log2FC=5.86; adjusted p=2.17e-27)
  • LOC105329265 (NCBI:GeneID:105329265): L-threonine 3-dehydrogenase, mitochondrial (log2FC=2.63; adjusted p=1.82e-25)
  • LOC105320131 (NCBI:GeneID:105320131): prostaglandin E2 receptor EP4 subtype (log2FC=2.20; adjusted p=9.13e-25)
  • LOC105321692 (NCBI:GeneID:105321692): cytochrome P450 2C31-like (log2FC=2.36; adjusted p=2.64e-23)
  • LOC105323667 (NCBI:GeneID:105323667): metalloproteinase inhibitor 2-like (log2FC=1.71; adjusted p=1.27e-22)
  • LOC105342835 (NCBI:GeneID:105342835): cAMP-responsive element modulator (log2FC=1.23; adjusted p=9.02e-22)
  • LOC105342241 (NCBI:GeneID:105342241): hypothetical protein (log2FC=6.70; adjusted p=1.05e-21)
  • LOC105326883 (NCBI:GeneID:105326883): serine/threonine-protein kinase TNNI3K (log2FC=1.78; adjusted p=2.8e-21)
  • LOC105333215 (NCBI:GeneID:105333215): ETS homologous factor (log2FC=1.33; adjusted p=1.45e-20)
  • LOC105338579 (NCBI:GeneID:105338579): cartilage matrix protein (log2FC=3.18; adjusted p=2.87e-19)
  • LOC105323642 (NCBI:GeneID:105323642): immediate early response gene 5-like protein (log2FC=1.11; adjusted p=5.89e-17)
  • LOC105322542 (NCBI:GeneID:105322542): interleukin 17-like protein (log2FC=4.10; adjusted p=1.25e-16)

Vibrio 12H Lower Fdr Lt 0.05

Genes: 374; RefSeq-characterized descriptions: 226 (60.4%).

  • LOC105329888 (NCBI:GeneID:105329888): argininosuccinate synthase (log2FC=-0.91; adjusted p=1.69e-10)
  • LOC105318596 (NCBI:GeneID:105318596): NPC intracellular cholesterol transporter 2 (log2FC=-0.84; adjusted p=1.55e-07)
  • LOC105337051 (NCBI:GeneID:105337051): von Willebrand factor A domain-containing protein 7 (log2FC=-1.37; adjusted p=2.57e-07)
  • LOC117683306 (NCBI:GeneID:117683306): metalloproteinase inhibitor 3 (log2FC=-1.54; adjusted p=3.92e-07)
  • LOC105331984 (NCBI:GeneID:105331984): sushi domain-containing protein 2 (log2FC=-1.17; adjusted p=9.47e-07)
  • LOC105328670 (NCBI:GeneID:105328670): deacetylase Oant_2987 (log2FC=-0.82; adjusted p=1.35e-06)
  • LOC105336022 (NCBI:GeneID:105336022): zinc finger TRAF-type-containing protein 1-B (log2FC=-0.67; adjusted p=1.87e-06)
  • LOC109620058 (NCBI:GeneID:109620058): macrophage-expressed gene 1 protein (log2FC=-0.61; adjusted p=5.56e-06)
  • LOC105342100 (NCBI:GeneID:105342100): putative leucine-rich repeat-containing protein DDB_G0290503 (log2FC=-1.18; adjusted p=5.56e-06)
  • LOC105335573 (NCBI:GeneID:105335573): hypothetical protein (log2FC=-0.56; adjusted p=9.78e-06)
  • LOC136274883 (NCBI:GeneID:136274883): tripartite motif-containing protein 2-like (log2FC=-2.11; adjusted p=1.49e-05)
  • LOC105340555 (NCBI:GeneID:105340555): serine/threonine-protein kinase PLK1 (log2FC=-0.61; adjusted p=2.66e-05)
  • LOC105320914 (NCBI:GeneID:105320914): regulator of chromosome condensation (log2FC=-0.86; adjusted p=2.81e-05)
  • LOC105331827 (NCBI:GeneID:105331827): serine-rich adhesin for platelets (log2FC=-1.06; adjusted p=3.96e-05)
  • LOC105322476 (NCBI:GeneID:105322476): macrophage mannose receptor 1 (log2FC=-1.00; adjusted p=6.1e-05)

Gene-biotype over-representation

One-sided hypergeometric tests compare each significant direction with all genes having DESeq2 results; Benjamini-Hochberg adjustment covers both directions and all biotypes.

  • vibrio 12h higher fdr lt 0.05: protein_coding (833 observed, 780.2 expected; fold=1.07; adjusted p=3.34e-12)

Many oyster loci retain automated or uncharacterized RefSeq labels. Functional claims should be based on formal ontology/pathway enrichment or orthology-aware analysis rather than names alone.