Evidence Card: NCBI:LOC105317002
Simulated demo evidence: This card does not describe real-study findings.
Status: Association evidence only; not a validated biomarker.
- Candidate score: 0.6128
- Ranking category: Multi-omics convergence candidate
- Species context: Crassostrea gigas
- Ortholog/reference context: ORTHO_IMMUNE_B
- Supporting studies: CGIG_HEAT_RNASEQ_001, CGIG_HEAT_RNASEQ_002, CGIG_PATH_PROTEO_001
- Assay types represented: gene, protein
- Phenotype/stressor/tissue contexts: disease_resistance / pathogen_challenge / hemolymph; survival / temperature / mantle; thermal_tolerance / temperature / gill
- Direction of association: down: 1, higher: 1, up: 1
- Identifier mapping confidence: exact, one-to-one ortholog
- Limitations: conflicting_direction; none
- Effects without usable uncertainty or with exploratory inference (not pooled in meta-analysis): none
Effect Summary
| study_id | feature_type | effect_size | standard_error | adjusted_p_value |
|---|---|---|---|---|
| CGIG_HEAT_RNASEQ_001 | gene | 0.9 | 0.28 | 0.03 |
| CGIG_HEAT_RNASEQ_002 | gene | -0.55 | 0.3 | 0.12 |
| CGIG_PATH_PROTEO_001 | protein | 0.95 | 0.27 | 0.018 |
Recommended Next Validation Step
Prioritize independent biological replication with matched phenotype definitions and targeted validation in the relevant tissue and life stage.